Guide to Pill Splitting

Medically Reviewed by Nayana Ambardekar, MD on August 13, 2022

Some people can split their pills in half to save money on prescription drugs. If your medicine is available in double your normal dose, and you can safely split the pills, you may be able to get a 2-month supply of medicine for the price of one.

But many medications can’t be split safely. The FDA has issued warnings about the risks. Professional societies representing pharmacists and doctors have as well.

So when is it safe?

It's important to talk to your doctor or pharmacist before you consider cutting your pills. In general, however, look for these three signs that a pill is safe to split:

  1. FDA approval. If the FDA has approved a drug for splitting, it will be printed on the package insert.
  2. Thumbs up from your doctor or pharmacist. Before splitting any pill, talk it over with your doctor or pharmacist.
  3. Scored down the middle. Scored pills are easier to split evenly. But a line down the middle doesn’t always mean it’s safe to split. Check with your doctor or pharmacist, or look for the FDA approval.

If a pill has any of these features, don’t try to cut it in half:

  • A hard outer coat: Splitting a coated pill can make it harder to swallow and may change the way your body absorbs the medicine.
  • They’re extended release: Pills formulated to give you medication slowly throughout the day may lose this capability if split in half.
  • They’re capsules: Because they contain powder or gel, capsules have to be taken whole.
  • A small or uneven shape: Some pills are just too difficult to split evenly.

Even if your doctor or pharmacist says your pills are safe to split, there can be problems. Think about these before you decide to try pill splitting:

  • The possibility of an uneven dose: For some drugs, the dose has to be so accurate even a small difference in two halves of a split pill could put your health at risk.
  • Crushed pill issues: Some pills can easily turn to powder. A pile of crumbs will be very difficult to break into two equal doses.
  • Miscommunication: Your doctor may write "1/2 pill" and your pharmacist may see "1 -- 2 pills."
  • Confusion: If you forget to split pills before taking them, you’ll take twice as much as your doctor intended.
  • Physical limitations: If a medical condition has made your hands weak or unsteady, or if your vision is impaired, it will be tough to split pills cleanly by yourself.

  • Use a pill splitter. They’re cheap -- between $3 and $10 at most pharmacies. Some health insurance providers will send them to members for free.
  • Keep it clean. Always wash your hands first. Wash the pill splitter thoroughly after you’ve done your splitting.
  • Ask your pharmacist for instructions. Some pills may lose their potency when their insides are exposed to heat or humidity. Some groups say only registered pharmacists should split pills. Others say you should split one pill at a time.

Show Sources

SOURCES:                                                                                                                              

Academy of Managed Care Pharmacy: "Professional Practice Advisory on Tablet Splitting."

FDA: "Consumer Updates -- Tablet Splitting: A Risky Practice."

American Society of Consultant Pharmacists: "Tablet Splitting for Cost Containment."

Grissinger M. Pharmacy and Therapeutics, February 2010.

American Medical News: "Cost vs. compliance: Physicians encouraged to discuss prescriptions."

Consumer Reports: "Pill Splitting."

Premera Blue Cross: "Save on Copays with Tablet Splitting Program."

UnitedHealthcare Half Tablet Program.

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