Myofascial Pain Syndrome (Muscle Pain)

Written by WebMD Editorial Contributors
Medically Reviewed by Sanjay Ponkshe on May 13, 2023

Myofascial pain syndrome (MPS) is a fancy way to describe muscle pain. It refers to pain and inflammation in the body's soft tissues.

MPS is a chronic condition that affects the fascia (connective tissue that covers the muscles). It may involve either a single muscle or a muscle group. In some cases, the area where a person experiences the pain may not be where the myofascial pain generator is located. Experts believe that the actual site of the injury or the strain prompts the development of a trigger point that, in turn, causes pain in other areas. This situation is known as referred pain.

Myofascial pain may develop from a muscle injury or from excessive strain on a particular muscle or muscle group, ligament or tendon. Other causes include:

  • Injury to muscle fibers
  • Repetitive motions
  • Lack of activity (such as having a broken arm in a sling)

 

Myofascial pain symptoms usually involve muscle pain with specific "trigger" or "tender" points. The pain can be made worse with activity or stress. In addition to the local or regional pain associated with myofascial pain syndrome, people with the disorder also can suffer from depression, fatigue and behavioral disturbances.

 

Trigger points can be identified by pain that results when pressure is applied to a specific area of a person's body. In the diagnosis of myofascial pain syndrome, two types of trigger points can be distinguished:

  • An active trigger point is an area of extreme tenderness that usually lies within the skeletal muscle and which is associated with a local or regional pain.
  • A latent trigger point is a dormant (inactive) area that has the potential to act like a trigger point. It may cause muscle weakness or restriction of movement.

 

Medications such as non-steroidal anti-inflammatories (such as diclofenac, ibuprofen or naproxen)acetaminophen or mild opioids may be used to treat myofascial pain. Medications for sleep, depression or muscle spasm (such as Tizanidine or cyclobenzaprine) are sometimes used, as well. Non-drug treatments may include:

  • Physical therapy
  • Myofascial release therapy
  • "Stretch and spray" technique: This treatment involves spraying the muscle and trigger point with a coolant and then slowly stretching the muscle.
  • Massage therapy
  • Trigger point injection

In some chronic cases of myofascial pain, combinations of physical therapy, myofascial release therapy, trigger point injections, or massage are needed.